long-chain-fatty-acid-CoA ligase 4 isoform 2; acyl-CoA synthetase long chain family member 4
Reactivity
Hamster
Assay Type
Quantitative Sandwich
Description
The kit is designed to analyse the presence of the target Acyl Coenzyme A Synthetase Long Chain Family, Member 4 (ACSL4) in Hamster biological samples using enzyme-linked immunosorbent assay technology.
Sample Type
Serum, Plasma, Cell Culture Supernates, Cell Lysates, Tissue Homogenates and Other Biological Fluids.
Belongs to the ATP-dependent AMP-binding enzyme family.
Cellular Localization
Cell membrane, Endoplasmic reticulum and Membrane.
Function
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590).
Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590).
Modulates prostaglandin E2 secretion (PubMed:21242590).