13-Oxyingenol-13-dodecanoate

Cat. No. NATM-2505-CXX-12

Package 50 mg/100 mg/250 mg

Description

13-Oxyingenol-dodecanoate (13OD) is a tumor suppressor with anti-HIV-1 activity (EC50= 33.7 nM). It induces ULK1 expression, leading to mitochondrial dysfunction and cellular autophagy. Additionally, 13OD increases BAX expression and suppresses BCL-2 to promote apoptosis.

Product Details

Formula	C32H50O7
Molecular Weight	546.74
SMILES	CCCCCCCCCCCC(O[C@@]12C[C@@H](C)[C@@](C=C(C)[C@@H]3O)(C4=O)[C@]3(O)[C@H](O)C(CO)=C[C@@]4([H])[C@]1([H])C2(C)C)=O
Appearance	Solid
Color	White to off-white
Biological Target	HIV; ULK; Bcl-2 Family
Initial Source	Plants; Gramineae; Leptochloa chinensis (Linn.) Nees
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month