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17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor targeting 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), a multifunctional mitochondrial enzyme. It has no mitochondrial off-target, cytotoxic, or neurotoxic effects. 17β-HSD10 inhibitors are useful for Alzheimer's disease (AD) and hormone-dependent cancer research.
Formula | C15H10ClN3O4S |
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Molecular Weight | 363.78 |
SMILES | O=C(NC1=CC=C(C(Cl)=C1)O)NC2=NC3=CC=C(C(O)=O)C=C3S2 |
Biological Target | Endogenous Metabolite |
Target | 17β-HSD10 |
Initial Source | Endogenous metabolite |
Shipping Conditions | Room Temperature |
Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |