2'-Aminoacetophenone

Cat. No. NATM-2505-CXX-19

Package 1 g/5 g/10 g/50 g

Description

2'-Aminoacetophenone is an orally active inducer of apoptosis and a respiratory biomarker. It detects Pseudomonas aeruginosa infections in cystic fibrosis patients, inhibits LC3BII and p62 in infected macrophages, and regulates autophagy. It can disrupt mitochondrial function by inducing oxidative stress and apoptosis signaling, causing dysfunction in mouse skeletal muscle.

Product Details

Synonyms	o-aminoacetophenone
Purity	99.67%
Formula	C8H9NO
Molecular Weight	135.16
SMILES	CC(C1=CC=CC=C1N)=O
Appearance	<20°C Solid, >20°C Liquid
Color	Light yellow to yellow
Biological Target	Bacterial; Apoptosis; Atg8/LC3; p62; Autophagy
Initial Source	Microorganisms; Pseudomonas aeruginosa
Solubility	DMSO: 100 mg/mL (739.86 mM, need ultrasonic)
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month