2'-epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside from Cerbera manghas L. seeds, inhibits cell viability, induces apoptosis, and causes mitochondrial membrane potential loss in HepG2 cells.
| Synonyms | GHSC-74 |
|---|---|
| Formula | C44H68O19 |
| Molecular Weight | 901.00 |
| SMILES | O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@@H](C(CO4)=CC4=O)CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)OC)OC(C)=O)([H])CC3)C |
| Biological Target | Apoptosis |
| Initial Source | Plants; Apocynaceae; Cerbera manghas Linn. |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
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