2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde), a natural compound from Cinnamomum cassia, inhibits topoisomerase-I/II and NF-κB signaling. It causes mitochondrial dysfunction, induces lysosomal vesiculation, and leads to DNA damage and cell apoptosis, exhibiting antitumor effects.
| Synonyms | o-Methoxycinnamaldehyde |
|---|---|
| Purity | 0.98 |
| Formula | C10H10O2 |
| Molecular Weight | 162.19 |
| SMILES | O=C/C=C/C1=CC=CC=C1OC |
| Appearance | Solid |
| Color | White to yellow |
| Biological Target | Apoptosis; NF-κB; Topoisomerase; Mitochondrial Metabolism; Caspase |
| Initial Source | Plants; Lauraceae; Cinnamomum cassia (L.) D. Don |
| Solubility | DMSO: 100 mg/mL (616.57 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
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