6PPD-Q

Cat. No. NATM-2505-CXX-29

Package 5 mg/10 mg/25 mg/50 mg/100 mg/200 mg/500 mg

Description

6PPD-Q (6PPD-Quinone) is a ubiquitous environmental pollutant found in human urine. It targets CNR2, CNR1, AA2AR, LCAT, and TRPA1, with highest affinity for CNR2, potentially acting as a CNR2 receptor agonist. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. It is applicable for research in environmental toxicology, neurodegenerative diseases, and inflammation-related disorders.

Product Details

Synonyms	6PPD-Quinone
Purity	99.30%
Formula	C18H22N2O2
Molecular Weight	298.38
SMILES	O=C1C(NC(C)CC(C)C)=CC(C(NC2=CC=CC=C2)=C1)=O
Appearance	Solid
Color	Pink to red
Biological Target	α-synuclein
Target	α-synuclein Aggregation
Initial Source	Endogenous metabolite
Solubility	DMSO: 5 mg/mL (16.76 mM, ultrasonic and warming and heat to 60°C)
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month