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alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis, and inhibits PI3K/Akt signaling. It protects against Cisplatin-induced nephrotoxicity by mitigating inflammation and oxidative stress via NFκB inhibition. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic, and anticancer activities.
Purity | 0.8 |
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Formula | C15H26O |
Molecular Weight | 222.37 |
SMILES | C/C(C)=C\CC[C@@](O)([C@@H]1CCC(C)=CC1)C |
Appearance | Liquid |
Color | Less to light yellow |
Biological Target | PI3K; Apoptosis |
Target | PI3K |
Initial Source | Plants; other families |
Solubility | DMSO: 100 mg/mL (449.70 mM, need ultrasonic) |
Shipping Conditions | Room Temperature |
Storage Information | Pure form: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month |