The major bioactive component of Andrographis paniculata, demonstrating anti-inflammatory, anti-apoptotic, antiviral, and antiproliferative effects in vitro and in vivo. Irreversible antagonist of NF-κB and AP-1 (IC50 = 15 µM).
| Purity | >98% |
|---|---|
| CAS Number | 5508-58-7 |
| Formula | C20H30O6 |
| Molecular Weight | 350.45 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 25 mg/mL) or in ethanol (up to 8 mg/mL). |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to 25 mg/mL) or in Ethanol (up to 8 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or Ethanol can be stored at -20°C for up to 3 months. |
| Storage Information | -20°C |
Induces mitochondrial-mediated apoptosis
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