Annonacin

Cat. No. NATM-2505-CXX-41

Package 1 mg/5 mg/10 mg

Description

Annonacin, an acetylgenin, is toxic by inhibiting the mitochondrial complex pathway. It increases tau phosphorylation in R406W+/+ mice and inhibits Na+/K+-ATPase and SERCA pumps. Annonacin significantly kills ovarian, cervical, breast, bladder, and skin cancer cells, inducing apoptosis via Bax and Caspase-3 pathways.

Product Details

Purity	0.97
Formula	C35H64O7
Molecular Weight	596.88
SMILES	O=C1O[C@@H](C)C=C1C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@@H]2O[C@@H]([C@H](O)CCCCCCCCCCCC)CC2
Appearance	Solid
Color	White to off-white
Biological Target	Potassium Channel; Sodium Channel; Na+/K+ ATPase; Calcium Channel; Apoptosis
Initial Source	Plants; Annonaceae; Annona muricata Linn.
Shipping Conditions	Room Temperature
Storage Information	4°C, protect from light