(-)-Asarinin

Cat. No. NATM-2505-CXX-1

Package 1 mg/5 mg/10 mg/20 mg/50 mg/100 mg

Description

This tetrahydrofurofurano lignan has diverse biological activities, including inducing apoptosis in cancer cells, promoting mitochondrial ROS accumulation, inhibiting the STAT3 pathway, and suppressing mast cell activation as an Src family kinase inhibitor. It also acts as a non-competitive Δ5-desaturase inhibitor (Ki= 0.28 mM) and offers pain relief, antiviral, antiallergic, anti-tuberculous, and antitumor effects.

Product Details

Purity	99.90%
Formula	C20H18O6
Molecular Weight	354.35
SMILES	[H][C@]12[C@](CO[C@@H]2C3=CC=C(OCO4)C4=C3)([H])[C@H](C5=CC=C(OCO6)C6=C5)OC1
Appearance	Solid
Color	White to off-white
Biological Target	Apoptosis; Reactive Oxygen Species; STAT; Src; Stearoyl-CoA Desaturase (SCD); Bacterial
Initial Source	Plants; Aristolochiaceae; Asarum sieboldii Miq.
Solubility	DMSO: 100 mg/mL (282.21 mM, need ultrasonic)
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month