BT2 inhibits mitochondrial branched-chain α-ketoacid dehydrogenase complex kinase (BCKDC) with an IC50 of 3.19 µM. Inhibiting this kinase reduces in vivo levels of branched-chain amino acids.
| Formal Name | 3, 6-Dichlorobenzo[b]thiophene-2-carboxylic acid |
|---|---|
| Purity | >98% |
| CAS Number | 34576-94-8 |
| Formula | C9H4Cl2O2S |
| Molecular Weight | 247.1 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to at least 20 mg/mL) |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to at least 20 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 3 months. |
| Storage Information | -20°C |
BCKDC kinase inhibitor
Datasheet