CGP 57380

Cat. No. BIAOS-2505-CXX-12

Package 1 mg

Description

Low-molecular-weight MNK1/2 inhibitor (IC50 = 0.87 and 1.6 μM). Also inhibits other kinases: CKI (0.51 μM), Aurora B (2.5 μM), DYRK3 (3.2 μM), SGK1 (2.7 μM), BRSK2 (1.1 μM), and Lck (2.5 μM).

Product Details

Formal Name	3-N-(4-fluorophenyl)-2H-pyrazolo[3, 4-d]pyrimidine-3, 4-diamine
Synonyms	N3-(4-fluorophenyl)-1h-pyrazolo[3, 4-d]pyrimidine-3, 4-diamine
Purity	>98%
CAS Number	522629-08-9
Formula	C11H9FN6
Molecular Weight	244.23
Appearance	Solid
Stability	Stable for 12 months
Storage Information	4°C

Application

MNK inhibitor