Citronellol (Standard) is the analytical standard for Citronellol. This orally active apoptosis inducer prevents oxidative stress, mitochondrial dysfunction, and apoptosis in the 6-OHDA-induced SH-SY5Y Parkinson's disease model by regulating ROS-NO, MAPK/ERK, and PI3K/Akt pathways. It induces necroptosis in human lung cancer cells via the TNF-α pathway and ROS accumulation. Citronellol reduces LC-3 and p62 levels to regulate autophagy, inhibits oxidative stress and neuroinflammation, providing neuroprotective effects in Parkinson's rats. It also exhibits antifungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis.
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