CYP11B2 Protein, Human (His-SUMO), a cytochrome P450 monooxygenase, synthesizes aldosterone, crucial for salt/water balance. This recombinant human CYP11B2, expressed in E. coli with N-6*His and N-SUMO tags, orchestrates three oxidative reactions and may also be involved in androgen metabolism.
| Purity | Greater than 90% as determined by reducing SDS-PAGE. |
|---|---|
| Molecular Weight | 66 kDa |
| Appearance | Lyophilized Powder |
| Formulation | Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4 |
| Species | Human |
| Source | E. coli |
| Accession | P19099 (G25-N503) |
| Gene ID | 1585 |
| Alternative Names | ALDOS; Aldosterone synthase; Aldosterone-synthesizing enzyme; C11B2_HUMAN; CYP11B2; CYPXIB2; Cytochrome P-450Aldo; Cytochrome P-450C18; Cytochrome P450 11B2; Cytochrome P450 11B2; mitochondrial; mitochondrial; P-450Aldo; P-450C18; Steroid 18-hydroxylase |
| Tag | N-6*His; N-SUMO |
| Endotoxin Level | <1 EU/μg, determined by LAL method. |
| Biological Activity | Enzyme activity of this recombinant protein is currently under evaluation, so we cannot provide a guarantee. |
| Shipping Conditions | Room Temperature |
| Storage Information | Store at -20°C for up to 2 years from the date of receipt. After reconstitution, it's stable at 4°C for 1 week or -20°C for longer (with carrier protein). For extended storage, freeze in aliquots at -20°C or -80°C. |
Datasheet