Dephospho-CoA is a key intermediate in CoA biosynthesis, where GTP-dependent DPCK catalyzes its conversion to CoA. It completes CoA's final synthesis via phosphorylation, participating in energy metabolism and cell signaling. Dephospho-CoA is useful in cancer research (e.g., regulating cell proliferation) and metabolic diseases (e.g., mitochondrial dysfunction).
| Purity | 96% |
|---|---|
| Formula | C21H35N7O13P2S |
| Molecular Weight | 687.55 |
| SMILES | O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2 |
| Appearance | Solid |
| Color | White to off-white |
| Biological Target | Endogenous Metabolite |
| Target | Human Endogenous Metabolite |
| Initial Source | Endogenous metabolite; Human Gut Microbiota Metabolites |
| Solubility | H2O: 50 mg/mL (72.72 mM, need ultrasonic and warming) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
Datasheet