Desmosterol (Standard)

Cat. No. NATM-2505-CXX-70

Package 50 mg/100 mg/250 mg

Description

Desmosterol (Standard) is the analytical standard for Desmosterol, intended for research and analytical use. This cholesterol-like molecule is a direct precursor in the Bloch pathway of cholesterol biosynthesis and is used as an endogenous metabolite for cholesterol metabolism studies. It activates LXR and inhibits SREBP, suppressing macrophage inflammasome activation and preventing vascular inflammation and atherosclerosis. Reduced Desmosterol promotes mitochondrial ROS production in macrophages and NLRP3 inflammasome activation. It holds potential for research in inflammation, metabolism, and cardiovascular diseases.

Product Details

Purity	0.98
Formula	C27H44O
Molecular Weight	384.64
SMILES	C/C(C)=C\CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Target	Endogenous Metabolite; LXR; Fatty Acid Synthase (FASN); Interleukin Related; Reactive Oxygen Species; NOD-like Receptor (NLR)
Initial Source	Endogenous metabolite; Disease markers; Endocrine diseases; Microorganisms
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month