Dihydrorotenone, a natural pesticide, is a potent mitochondrial inhibitor that likely induces Parkinsonian syndrome. It induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating the p38 signaling pathway.
| Purity | 99.66% |
|---|---|
| Formula | C23H24O6 |
| Molecular Weight | 396.43 |
| SMILES | O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C(O[C@@H](C(C)C)C5)=CC=C14 |
| Appearance | Solid |
| Color | White to off-white |
| Biological Target | Mitochondrial Metabolism; Apoptosis |
| Initial Source | Plants; Convolvulaceae; Erycibe ferruginea C. Y. Wu |
| Solubility | DMSO: 25 mg/mL (63.06 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
Datasheet