Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative extracted from Phyllopteris officinalis. It exhibits antitumor and antiviral activity, inducing apoptosis in human hepatocellular carcinoma cells via a caspase-mediated mitochondrial pathway.
| Synonyms | Dryocrassin |
|---|---|
| Purity | 0.95 |
| Formula | C43H48O16 |
| Molecular Weight | 820.83 |
| SMILES | OC1=C(C(O)=C(C(CCC)=O)C(O)=C1CC(C(C(C(C)=O)=C(O)C2(C)C)=O)=C2O)CC(C(O)=C(C(CCC)=O)C(O)=C3CC(C(C(C(C)=O)=C(O)C4(C)C)=O)=C4O)=C3O |
| Appearance | Solid |
| Color | Light yellow to green yellow |
| Biological Target | Apoptosis; Influenza Virus |
| Initial Source | Plants; Dryopteridaceae; Dryopteris crassirhizoma Nakai |
| Solubility | DMSO: 16.67 mg/mL (20.31 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
Datasheet