Dynasore is a noncompetitive inhibitor of dynamin GTPase activity, blocking dynamin-dependent endocytosis in cells, including neurons. It inhibits dynamin1, dynamin2, and Drp1 (mitochondrial dynamin).
| Formal Name | 3-Hydroxynaphthalene-2-carboxylic acid (3, 4-dihydroxybenzylidene)hydrazide |
|---|---|
| Purity | >98% |
| CAS Number | 304448-55-3 |
| Formula | C18H14N2O4 |
| Molecular Weight | 322.32 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 30 mg/mL), or in ethanol (up to 1 mg/mL). |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to 30 mg/mL), or in Ethanol (up to 1 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20° for up to 1 month. |
| Storage Information | -20°C |
Dynamin inhibitor
Datasheet