A ferroptosis inducer that inhibits the cystine-glutamate antiporter system Xc-, activating ER stress response. Also blocks mitochondrial voltage-dependent anion channels VDAC2 and VDAC3.
| Formal Name | 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone |
|---|---|
| Purity | >98% |
| CAS Number | 571203-78-6 |
| Formula | C30H31ClN4O4 |
| Molecular Weight | 547.04 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 10 mg/mL with warming). |
| Stability | ≥ 1 year |
| Application Procedures | First, dissolve in DMSO (up to 10 mg/mL with warming), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 3 months. |
| Storage Information | -20°C |
Ferroptosis inducer
Datasheet