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EX-527

Cat. No. BIAOS-2505-CXX-19

Package 1 mg

Datasheet

Description

Selective, cell-permeable SIRT1 inhibitor (IC50 = 98 nM for SIRT1). Does not affect other HDACs or SIRTs. Enhances p53 acetylation in response to DNA-damaging agents.

Product Details

Formal Name 6-chloro-2, 3, 4, 9-tetrahydro-1H-carbazole-1-carboxamide
Synonyms 6-chloro-2, 3, 4, 9-tetrahydro-1H-carbazole-1-carboxamide
Purity >97%
CAS Number 49843-98-3
Formula C13H13ClN2O
Molecular Weight 248.71
Appearance Solid
Stability Store in the dark; store under desiccating conditions
Storage Information -20°C

Application

SIRT1 inhibitor