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Selective, cell-permeable SIRT1 inhibitor (IC50 = 98 nM for SIRT1). Does not affect other HDACs or SIRTs. Enhances p53 acetylation in response to DNA-damaging agents.
| Formal Name | 6-chloro-2, 3, 4, 9-tetrahydro-1H-carbazole-1-carboxamide |
|---|---|
| Synonyms | 6-chloro-2, 3, 4, 9-tetrahydro-1H-carbazole-1-carboxamide |
| Purity | >97% |
| CAS Number | 49843-98-3 |
| Formula | C13H13ClN2O |
| Molecular Weight | 248.71 |
| Appearance | Solid |
| Stability | Store in the dark; store under desiccating conditions |
| Storage Information | -20°C |
SIRT1 inhibitor