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Selective, cell-permeable SIRT1 inhibitor (IC50 = 98 nM for SIRT1). Does not affect other HDACs or SIRTs. Enhances p53 acetylation in response to DNA-damaging agents.
Formal Name | 6-chloro-2, 3, 4, 9-tetrahydro-1H-carbazole-1-carboxamide |
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Synonyms | 6-chloro-2, 3, 4, 9-tetrahydro-1H-carbazole-1-carboxamide |
Purity | >97% |
CAS Number | 49843-98-3 |
Formula | C13H13ClN2O |
Molecular Weight | 248.71 |
Appearance | Solid |
Stability | Store in the dark; store under desiccating conditions |
Storage Information | -20°C |
SIRT1 inhibitor