Fuscin, a fungal metabolite, is a CCR5 receptor antagonist with anti-HIV effects. It inhibits respiration, oxidative phosphorylation, and mitochondrial SH-dependent transport functions.
| Formula | C15H16O5 |
|---|---|
| Molecular Weight | 276.28 |
| SMILES | O=C1C=C2C(C(C)O1)=C(O)C(C3=C2CCC(C)(C)O3)=O |
| Biological Target | Oxidative Phosphorylation; CCR; HIV; Bacterial; Mitochondrial Metabolism; Endogenous Metabolite |
| Target | HIV; CCR5; Microbial Metabolite |
| Initial Source | Microorganisms; soil fungus Oidiodendron griseum |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
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