Ganoderic acid T1

Cat. No. NATM-2505-CXX-92

Package 50 mg/100 mg/250 mg

Description

Ganoderic acid T1, a deacetylated derivative of Ganoderic acid T, attenuates the antioxidant defense system and induces cancer cell apoptosis. It decreases mitochondrial membrane potential and activates caspase-9 and caspase-3, triggering apoptosis. Ganoderic acid T1 also increases intracellular ROS generation, leading to pro-oxidant activities and cytotoxicity.

Product Details

Formula	C34H50O7
Molecular Weight	570.76
SMILES	C[C@]12C3=CCC4C([C@H](OC(C)=O)CC[C@@]4(C3=CC[C@]1(C)C([C@@H]([C@H](C/C=C(C(O)=O)\C)O)C)C[C@@H]2OC(C)=O)C)(C)C
Biological Target	Apoptosis; Caspase
Target	Caspase 3; Caspase-9
Initial Source	Microorganisms; Ganoderma lucidum
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month