A Platelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM) that inhibits neutrophil degranulation and superoxide production in vitro. Protects against focal cerebral ischemia by inhibiting the mitochondrial apoptotic pathway.
| Formal Name | Natural product isolated from Ginko biloba |
|---|---|
| Synonyms | BN 52021 |
| Purity | >98% |
| CAS Number | 15291-77-7 |
| Formula | C20H24O10 |
| Molecular Weight | 424.41 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 40 mg/mL) or in ethanol (up to 10 mg/mL). |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to 40 mg/mL) or in Ethanol (up to 10 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or Ethanol can be stored at -20°C for up to 3 months. |
| Storage Information | -20°C |
PAF antagonist
Datasheet