This naturally occurring antagonist of dihydrostreptomycin is a potent inhibitor of the respiratory chain binding to mitochondrial cytochrome b protein. It inhibits NADH oxidase and Na±dependent NADH-quinone reductase (NQR).
| Formal Name | 2-n-Heptyl-4-hydroxyquinoline N-oxide |
|---|---|
| Purity | >98% |
| CAS Number | 341-88-8 |
| Formula | C16H21NO2 |
| Molecular Weight | 259.25 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 8 mg/mL with warming), or in ethanol (up to 13 mg/mL with warming). |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to 8 mg/mL with warming), or in Ethanol (up to 13 mg/mL with warming), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20° for up to 1 month. |
| Storage Information | -20°C |
NADH oxidase inhibitor
Datasheet