Originally a potent antitumor agent targeting the G1 phase by suppressing CDK2 and cyclin E expression. It induced metabolome changes and mitochondrial dysfunction in neuroblastoma models, leading to complete tumor regression.
| Formal Name | 4-N-(3-Chloro-1H-indol-7-yl)benzene-1, 4-disulfonamide |
|---|---|
| Synonyms | E7070 |
| Purity | >98% |
| CAS Number | 165668-41-7 |
| Formula | C14H12ClN3O4S2 |
| Molecular Weight | 385.8 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 25 mg/mL) |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (25 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 1 month. |
| Storage Information | -20°C |
RBM39 Molecular glue
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