Isochamaejasmin

Cat. No. NATM-2505-CXX-106

Package 50 mg/100 mg/250 mg

Description

Isochamaejasmin, a biflavonoid, exhibits anticancer, antiplasmodial, and insecticidal activities. It potently activates NF-κB and causes DNA damage, inducing apoptosis via the mitochondrial pathway in AW1 cells. It also shows moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) with relatively low cytotoxicity (CC50 of 29.0 μM).

Product Details

Formula	C30H22O10
Molecular Weight	542.49
SMILES	O=C1[C@]([C@]2([H])[C@@H](C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C4C2=O)([H])[C@H](C5=CC=C(O)C=C5)OC6=CC(O)=CC(O)=C16
Biological Target	NF-κB; DNA/RNA Synthesis; Parasite; Apoptosis
Initial Source	Plants; Thymelaeaceae; Stellera chamaejasme Linn.; Plants; Urticaceae; Stellera chamaejasme Linn.
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month