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A potent and selective ATM kinase inhibitor. Disruption of ATM signaling leads to ribonucleotide reductase dysregulation and increased resistance to mitochondrial respiration and translation inhibitors.
Formal Name | 2-(4-Morpholinyl)-6-(1-thiamthrenyl)-4H-pyran-4-one |
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Purity | >98% |
CAS Number | 587871-26-9 |
Formula | C21H17NO3S2 |
Molecular Weight | 395.5 |
Appearance | Powder |
Solubility | Dissolves in DMSO (up to 40 mg/mL) or in ethanol (up to 20 mg/mL) |
Stability | ≥ 2 years |
Application Procedures | First, dissolve in DMSO (up to 40 mg/mL) or in Ethanol (up to 20 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20° for up to 1 month. |
Storage Information | -20°C |
ATM Kinase inhibitor