L-2-Hydroxyglutaric acid (disodium) (Standard)

Cat. No. NATM-2505-CXX-112

Package 1 mg/5 mg/10 mg/25 mg/50 mg/100 mg

Description

L-2-Hydroxyglutaric acid (disodium) (Standard) is the analytical standard for L-2-Hydroxyglutaric acid (disodium), intended for research and analytical applications. This epigenetic modifier and putative oncometabolite in renal cancer inhibits histone demethylases, promoting histone methylation. It also inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki values of 2.52 mM and 11.13 mM, respectively.

Product Details

Synonyms	(S)-2-Hydroxyglutaric acid (disodium) (Standard)
Purity	0.98
Formula	C5H6Na2O5
Molecular Weight	192.08
SMILES	O=C(O[Na])[C@@H](O)CCC(O[Na])=O
Appearance	Solid
Color	White to off-white
Biological Target	Histone Demethylase; Mitochondrial Metabolism; Endogenous Metabolite
Initial Source	Endogenous metabolite
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month