L-2-Hydroxyglutaric acid (Standard)

Cat. No. NATM-2505-CXX-113

Package 50 mg/100 mg/250 mg

Description

L-2-Hydroxyglutaric acid (Standard) is the analytical standard for L-2-Hydroxyglutaric acid, for research and analytical applications. This epigenetic modifier and putative oncometabolite in renal cancer inhibits histone demethylases, promoting histone methylation. It also inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki values of 2.52 mM and 11.13 mM, respectively.

Product Details

Synonyms	(S)-2-Hydroxyglutaric acid (Standard)
Purity	0.98
Formula	C5H8O5
Molecular Weight	148.11
SMILES	O=C(O)[C@@H](O)CCC(O)=O
Biological Target	Histone Demethylase; Mitochondrial Metabolism; Endogenous Metabolite
Initial Source	Microorganisms; Endogenous metabolite
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month