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Ligustroside (Ligstroside), a secoiridoid derivative, significantly improves mitochondrial bioenergetics in early Alzheimer's disease (AD) and brain aging models, possibly without interfering with Aβ production. It also significantly inhibits nitric oxide production in LPS-activated RAW264.7 macrophages.
| Synonyms | Ligstroside |
|---|---|
| Purity | 0.98 |
| Formula | C25H32O12 |
| Molecular Weight | 524.51 |
| SMILES | OC(C=C1)=CC=C1CCOC(C[C@H]2/C([C@@H](OC=C2C(OC)=O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=C\C)=O |
| Appearance | Solid |
| Color | White to off-white |
| Biological Target | Mitochondrial Metabolism |
| Initial Source | Plants; Oleaceae; Ligustrum japonicum Thunb. |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |