Alpha-lipoic acid is an endogenous antioxidant that increases hepatic nuclear Nrf2 levels, induces Nrf2-mediated gene transcription, and reverses age-related declines in hepatic glutathione in rats. It’s a crucial cofactor for several mitochondrial enzymes.
| Formal Name | 1, 2-dithiolane-3-pentanoic acid, racemic |
|---|---|
| Synonyms | Thioctic acid |
| Purity | >98% |
| CAS Number | 1077-28-7 |
| Formula | C8H14O2S2 |
| Molecular Weight | 206.3 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to at least 30 mg/mL) |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to at least 30 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored under an inert atmosphere at -20°C for up to 1 month. |
| Storage Information | -20°C |
Endogenous antioxidant and cofactor
Datasheet