α-Lipoic Acid (Thioctic acid) sodium is an antioxidant and a key cofactor for mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces ER stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 to create the CPUL1-LA NA nanoaggregate, enhancing antitumor efficacy.
| Synonyms | Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium |
|---|---|
| Purity | 99.92% |
| Formula | C8H13NaO2S2 |
| Molecular Weight | 228.31 |
| SMILES | O=C(O[Na])CCCCC1SSCC1 |
| Appearance | Solid |
| Color | White to off-white |
| Biological Target | NF-κB; HIV; Mitochondrial Metabolism; Endogenous Metabolite; Apoptosis |
| Target | HIV-1; NF-κB; Human Endogenous Metabolite; Microbial Metabolite |
| Initial Source | Endogenous metabolite |
| Solubility | H2O: 35 mg/mL (153.30 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Store at room temperature, keep dry and cool |
Datasheet