An orally active, blood-brain barrier-permeant nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist that promotes survival signaling in neurotrophin-responsive cells. It stabilizes neuronal calcium, preserves mitochondrial movement, and protects against HIV-associated neuropathogenesis.
| Formal Name | (2S, 3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide, dihydrochloride |
|---|---|
| Purity | >98% |
| CAS Number | 1243259-19-9 |
| Formula | C12H25N3O2 2HCl |
| Molecular Weight | 316.27 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 20 mg/mL) or in water (up to 30 mg/mL). |
| Stability | ≥ 1 year |
| Application Procedures | First, dissolve in DMSO (up to 20 mg/mL) or in Water (up to 30 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20°C for up to 1 month. |
| Storage Information | -20°C |
p75NTR ligand. Promotes neurogenesis
Datasheet