Mdivi-1 is a selective inhibitor of Dnm1 GTPase (IC50 = 1–10 μM). It inhibits mitochondrial outer membrane permeabilization, mitochondrial division, and apoptosis.
| Formal Name | 3-(2, 4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone |
|---|---|
| Synonyms | Mdivi-1 |
| Purity | >98% |
| CAS Number | 338967-87-6 |
| Formula | C15H10Cl2N2O2S |
| Molecular Weight | 353.23 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 25 mg/mL) |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to 25 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 3 months. |
| Storage Information | -20°C |
Mitochondrial division inhibitor
Datasheet