Mito-lonidamine, conjugated to a triphenylphosphonium moiety, effectively targets mitochondria. It is a tumor-selective inhibitor of oxidative phosphorylation, inhibiting mitochondrial bioenergetics in lung cancer cells.
| Formal Name | (10-(1-(2, 4-Dichlorobenzyl)-1H-indazole-3-carboxamido)decyl)triphenylphosphonium bromide |
|---|---|
| Purity | >98% |
| CAS Number | 2361564-49-8 |
| Formula | C43H45BrCl2N3OP |
| Molecular Weight | 801.6 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (30 mg/mL) |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (30 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 3 months. |
| Storage Information | -20°C |
Mitochondria-targeted antiglycolytic agent
Datasheet