Monomethyl lithospermate

Cat. No. NATM-2505-CXX-134

Package 50 mg/100 mg/250 mg

Description

Monomethyl lithospermate activates the PI3K/AKT pathway, protecting against nerve injury. It improves SHSY-5Y cell survival, inhibits mitochondrial membrane potential (MMOP) breakdown, and suppresses cell apoptosis. It also reduces oxidative stress in rat brain tissue following middle artery occlusion (MCAO) and improves nerve damage in rats with ischemic stroke (IS).

Product Details

Synonyms	Lithospermic acid monomethyl ester
Formula	C28H24O12
Molecular Weight	552.48
SMILES	O=C(/C=C/C1=C2C(O[C@@H]([C@H]2C(OC)=O)C3=CC(O)=C(O)C=C3)=C(O)C=C1)O[C@H](CC4=CC(O)=C(O)C=C4)C(O)=O
Biological Target	Akt
Initial Source	Plants; Leguminosae; Samanea saman (Jacq.) Merr.; Plants; Labiatae
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month