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MOTS-c (human)

Cat. No. MRP-2505-CXX-20

Package 5 mg/10 mg/50 mg/100 mg

Datasheet

Description

Human MOTS-c is a blood-brain barrier-penetrating, mitochondrial-derived peptide that enhances insulin sensitivity by modulating the AMPK/PGC-1α pathway. It inhibits the folate cycle and de novo purine synthesis, increases AICAR to activate AMPK, regulates the Nrf2/Keap1 antioxidant pathway, inhibits NF-κB inflammation, and promotes mitochondrial biogenesis and energy metabolism.

Product Details

Purity 99.90%
Formula C101H152N28O22S2
Molecular Weight 2174.59
Appearance Solid
Color White to off-white
Biological Target Apoptosis; GLUT; AMPK
Research Areas Neurological Disease, Metabolic Disease, Inflammation/Immunology, Endocrinology
Sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Sequence Shortening MRWQEMGYIFYPRKLR
Shipping Conditions Room Temperature
Storage Information Powder: -80°C (2 years), -20°C (1 year); In solvent: -80°C (6 months), -20°C (1 month)