MOTS-c(human) acetate

Cat. No. MRP-2505-CXX-22

Package 5 mg/10 mg/50 mg/100 mg/200 mg

Description

Human MOTS-c acetate is a blood-brain barrier-penetrating, mitochondrial-derived peptide that enhances insulin sensitivity by modulating the AMPK/PGC-1α pathway. It inhibits the folate cycle and de novo purine synthesis, increases AICAR to activate AMPK, regulates the Nrf2/Keap1 antioxidant pathway, inhibits NF-κB inflammation, and promotes mitochondrial biogenesis and energy metabolism.

Product Details

Purity	98.97%
Formula	C103H156N28O24S2
Molecular Weight	2234.64
Appearance	Solid
Color	White to off-white
Biological Target	AMPK; GLUT
Research Areas	Neurological Disease, Metabolic Disease, Inflammation/Immunology, Endocrinology
Sequence	Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Sequence Shortening	MRWQEMGYIFYPRKLR
Solubility	H2O: 6.25 mg/mL (2.80 mM, need ultrasonic); DMSO: 4 mg/mL (1.79 mM, need ultrasonic)
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C (2 years), -20°C (1 year); In solvent: -80°C (6 months), -20°C (1 month)