Mycothiazole

Cat. No. NATM-2505-CXX-136

Package 50 mg/100 mg/250 mg

Description

Mycothiazole inhibits mitochondrial electron transport chain (ETC) complex I. It exhibits cytotoxicity in cancer cells Huh7 (IC50 is 55.8 μM), U87, and MCF7, and induces apoptosis in Huh7. Mycothiazole extends C. elegans lifespan by utilizing UPR and HSR pathway transcription factors ATFS-1 and HSF1.

Product Details

Formula	C22H32N2O3S
Molecular Weight	404.57
SMILES	COC(NCCC(/C=C\C[C@H](O)C(C)(C1=NC(C/C=C\CC=C)=CS1)C)=C)=O
Biological Target	Mitochondrial Metabolism
Initial Source	Marine natural products; Sponge; marine sponge
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month