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Naphthazarin (DHNQ), a natural compound, exerts effects through various cellular mechanisms including oxidative stress, mitochondrial AIF activation, microtubule depolymerization, lysosomal dysfunction, and p53-dependent p21 activation. It triggers apoptosis and has antitumor effects.
| Synonyms | DHNQ; 5, 8-Dihydroxy-1, 4-naphthoquinone |
|---|---|
| Purity | 99.59% |
| Formula | C10H6O4 |
| Molecular Weight | 190.15 |
| SMILES | O=C1C=CC(C2=C1C(O)=CC=C2O)=O |
| Appearance | Solid |
| Color | Brown to black |
| Biological Target | Apoptosis |
| Initial Source | Plants; other families |
| Solubility | DMSO: 7.14 mg/mL (37.55 mM, ultrasonic and warming and heat to 60°C) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month |