NIM811 ((Melle-4)cyclosporin; SDZ NIM811) is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin. It shows potent in vitro activity against hepatitis C virus.
| Synonyms | (Melle-4)cyclosporin; SDZ NIM811 |
|---|---|
| Purity | 99.77% |
| Formula | C62H111N11O12 |
| Molecular Weight | 1202.61 |
| Appearance | Solid |
| Color | White to off-white |
| Biological Target | Cyclophilin; Mitochondrial Metabolism; HCV |
| Research Areas | Infection, Inflammation/Immunology |
| Solubility | DMSO: 100 mg/mL (83.15 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C (2 years), -20°C (1 year); In solvent: -80°C (6 months), -20°C (1 month) |
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