This monovalent cation ionophore selectively transports NH₄⁺ and K⁺, upregulates mitochondrial stress proteins HSP58 and GRP75, and abolishes mitochondrial membrane potential.
| Formal Name | Isolated from Streptomyces griseus |
|---|---|
| Synonyms | Polynactin; Werramycin A |
| Purity | >98% |
| CAS Number | 6833-84-7 |
| Formula | C40H64O12 |
| Molecular Weight | 736.95 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 10 mg/mL) or in ethanol (up to 10 mg/mL). |
| Stability | ≥ 1 year |
| Application Procedures | First, dissolve in DMSO (up to 10 mg/mL) or in Ethanol (up to 10 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20° for up to 2 months. |
| Storage Information | -20°C |
Monovalent cation ionophore (K+ and NH4+)
Datasheet