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A potent inhibitor of CDK1/cyclin B (IC50 = 9.5 nM) and CDK2/cyclin A3 (IC50 = 5.4 nM); antiproliferative agent. Inhibits CDK4/D1, DYRK1A, PDK1, ROCKII (IC50 = 1.6, 0.9, 0.8, 0.6 μM).
| Formal Name | 4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]benzenesulfonamide |
|---|---|
| Synonyms | O6-Cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine |
| Purity | >98% |
| CAS Number | 444722-95-6 |
| Formula | C18H22N6O3S |
| Molecular Weight | 402.5 |
| Appearance | Solid |
| Stability | Store in the dark; store under desiccating conditions |
| Storage Information | -20°C |
CDK1/cyclin B and CDK2/cyclin A3 inhibitor