OGDC-E Protein, Mouse (His-SUMO), a vital component of the 2-oxoglutarate dehydrogenase complex, drives the conversion of 2-oxoglutarate to succinyl-CoA in mitochondria, a pivotal Krebs cycle step. This recombinant mouse OGDC-E, expressed in E. coli with N-SUMO and N-6*His tags, uses thiamine diphosphate for decarboxylation and participates in nuclear histone succinylation with KAT2A.
| Purity | Greater than 90% as determined by reducing SDS-PAGE. |
|---|---|
| Molecular Weight | 54 kDa |
| Appearance | Lyophilized Powder |
| Formulation | Lyophilized after extensive dialysis against solution in 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0. |
| Species | Mouse |
| Source | E. coli |
| Accession | Q60597 (V695-S1023) |
| Gene ID | 18293 |
| Alternative Names | Ogdh; Kiaa4192; 2-oxoglutarate dehydrogenase; mitochondrial; EC 1.2.4.2; 2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase |
| Tag | N-SUMO; N-6*His |
| Endotoxin Level | <1 EU/μg, determined by LAL method. |
| Biological Activity | Enzyme activity of this recombinant protein is currently under evaluation, so we cannot provide a guarantee. |
| Shipping Conditions | Room Temperature |
| Storage Information | Store at -20°C for up to 2 years from the date of receipt. After reconstitution, it's stable at 4°C for 1 week or -20°C for longer (with carrier protein). For extended storage, freeze in aliquots at -20°C or -80°C. |
Datasheet