Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene with anti-inflammatory and insecticidal properties. In vitro, it improves Amyloid-β-induced oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress. In vivo, it alleviates myocardial hypertrophy in rats.
| Synonyms | 3-Oxooleanolic acid |
|---|---|
| Purity | 99.63% |
| Formula | C30H46O3 |
| Molecular Weight | 454.68 |
| SMILES | CC1(C)C(CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O |
| Appearance | Solid |
| Color | White to off-white |
| Biological Target | HIV; Autophagy; Ferroptosis; Amyloid-β |
| Target | HIV-1 |
| Initial Source | Plants; other families |
| Solubility | DMSO: 50 mg/mL (109.97 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 2 years; -20°C, 1 year |
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