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Inhibits mitochondrial F1F0 ATP synthase, decreasing cellular ATP levels. It induces autophagy and stimulates lysosome acidification.
Formal Name | From Streptomyces sp., mixture of Oligomycin A, B, and C |
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Purity | >98% |
CAS Number | 1404-19-9 |
Formula | C45H74O11 (for Oligomycin A) |
Molecular Weight | 791.1 |
Appearance | Powder |
Solubility | Dissolves in DMSO (up to 300 mg/mL) or in ethanol (up to 200 mg/mL) |
Stability | ≥ 2 years |
Application Procedures | First, dissolve in DMSO (up to 300 mg/mL) or in Ethanol (up to 200 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20°C for up to 3 months. |
Storage Information | -20°C |
Mitochondrial ATPase inhibitor