Piericidin A, a ubiquinone analog, is a potent inhibitor of mitochondrial and bacterial type I NADH-ubiquinone oxidoreductase (complex I), binding to the enzyme’s ubiquinone site.
| Formal Name | 2-(10-hydroxy-3, 7, 9, 11-tetramethyl-2, 4, 7, 11-tridecatetraenyl)-5, 6-dimethoxy-3-methyl-4-pyridinol |
|---|---|
| Synonyms | Piericidin A1; Shaoguanmycin B; SN 198E; AR-054 |
| Purity | >95% |
| CAS Number | 2738-64-9 |
| Formula | C26H37NO4 |
| Molecular Weight | 415.6 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 25 mg/mL) or in ethanol (up to 20 mg/mL) |
| Stability | ≥ 2 years |
| Application Procedures | First, dissolve in DMSO (up to 25 mg/mL) or in Ethanol (up to 20 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or Ethanol can be stored at -20°C for up to 1 month. |
| Storage Information | -20°C |
Mitochondrial complex I inhibitor; CoQ10 analog
Datasheet