Activates ATP-dependent potassium channels, inducing vascular relaxation and antihypertensive effects. Protects cerebellar granule neurons from oxidative stress-induced apoptosis by preventing loss of mitochondrial membrane potential.
| Formal Name | (+/-)-N-Cyano-N’-4-pyridinyl-Nα-(1, 2, 2-trimethylpropyl)guanidine, monohydrate |
|---|---|
| Purity | >98% |
| CAS Number | 85371-64-8 |
| Formula | C13H19N5 H2O |
| Molecular Weight | 263.34 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 25 mg/mL with warming) or in ethanol (up to 25 mg/mL with warming) |
| Stability | ≥ 1 year |
| Application Procedures | First, dissolve in DMSO (up to 25 mg/mL with warming) or in Ethanol (up to 25 mg/mL with warming), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20°C for up to 2 months. |
| Storage Information | Room Temperature |
Potassium channel opener
Datasheet